DNA STRUCTURE DISCOVERED
February 28, 1953 - Cambridge, MA, U.S.A.
James Watson, from early on this Saturday, spent his time at the Cavendish Laboratory in Cambridge, shuffling cardboard cutout models of the molecules of the DNA bases: adenine (A), guanine (G), cytosine (C) and thymine(T). After a while, in a spark of ingenuity, he discovered their complementary pairing. He realized that A joined with T had a close resemblance to C joined with G, and that each pair could hold together with hydrogen bonds. Such pairs could also neatly fit like rungs meeting at right-angles between two anti-parallel helical sugar-phosphate backbones of DNA wound around a common axis. Such structure was consistent with the known X-ray diffraction pattern evidence. Each separated helix with its half of the pairs could form a template for reproducing the molecule. The secret of life!
BALTIMORE & OHIO RAILROAD
February 28, 1827 - Baltimore & Ohio USA
The Baltimore & Ohio Railroad became the first U.S. railway chartered for the commercial transportation of freight and passengers. Investors hoped that a railroad would allow Baltimore, the second largest U.S. city at that time, to successfully compete with New York for western trade. New Yorkers were profiting from easy access to the Midwest via the Erie Canal.
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RANDOM QUOTES
Happiness
by Thomas Jefferson
"...Our greatest happiness does not depend on the condition of life in which chance has placed us, but is always the result of a good conscience, good health, occupation, and freedom in all just pursuits...."
No Man is Above the Law
by Theodore Roosevelt
"..."No man is above the law and no man is below it; nor do we ask any man's permission when we require him to obey it. Obedience to the law is demanded as a right; not asked as a favor."..."
RANDOM FACTS
Salary
about Steve Jobs
Steve Jobs' annual salary was $1, just enough to keep company health benefits.
Cancer Facts & Figures
about Besides Lung Cancer
Besides lung cancer, tobacco use also increases the risk for cancers of the mouth, lips, nasal cavity (nose) and sinuses, larynx (voice box), pharynx (throat), esophagus (swallowing tube), stomach, pancreas, kidney, bladder, uterus, cervix, colon/rectum, ovary (mucinous), and acute myeloid leukemia.
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