DNA STRUCTURE DISCOVERED
February 28, 1953 - Cambridge, MA, U.S.A.
James Watson, from early on this Saturday, spent his time at the Cavendish Laboratory in Cambridge, shuffling cardboard cutout models of the molecules of the DNA bases: adenine (A), guanine (G), cytosine (C) and thymine(T). After a while, in a spark of ingenuity, he discovered their complementary pairing. He realized that A joined with T had a close resemblance to C joined with G, and that each pair could hold together with hydrogen bonds. Such pairs could also neatly fit like rungs meeting at right-angles between two anti-parallel helical sugar-phosphate backbones of DNA wound around a common axis. Such structure was consistent with the known X-ray diffraction pattern evidence. Each separated helix with its half of the pairs could form a template for reproducing the molecule. The secret of life!
BALTIMORE & OHIO RAILROAD
February 28, 1827 - Baltimore & Ohio USA
The Baltimore & Ohio Railroad became the first U.S. railway chartered for the commercial transportation of freight and passengers. Investors hoped that a railroad would allow Baltimore, the second largest U.S. city at that time, to successfully compete with New York for western trade. New Yorkers were profiting from easy access to the Midwest via the Erie Canal.
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RANDOM QUOTES
Rules for Happiness
by Immanuel Kant
"...Rules for Happiness: Something to do, Someone to love, Something to hope for...."
A Change is Gonna Come
by Meredith Grey
"...Change; we don't like it, we fear it, but we can't stop it from coming. We either adapt to change, or we get left behind. It hurts to grow, anybody who tells you it doesn't is lying. But here's the truth: Sometimes the more things change, the more they stay the same. And sometimes, oh, sometimes change is good. Sometimes change is everything...."
RANDOM FACTS
Harvard Medical School
about Eyesight Myth and Fact
Myth: Staring at a computer screen all day is harmful to the eyes.
Fact: Spending the day staring at a screen can tire or strain your eyes, but it will not hurt them. Make sure lighting doesn't create a glare on your screen. When spending long periods at your keyboard, take a break now and then to rest your eyes to reduce fatigue. Also, don't forget to blink. Your eyes need to stay lubricated to feel comfortable.
Cancer Facts & Figures
about Besides Lung Cancer
Besides lung cancer, tobacco use also increases the risk for cancers of the mouth, lips, nasal cavity (nose) and sinuses, larynx (voice box), pharynx (throat), esophagus (swallowing tube), stomach, pancreas, kidney, bladder, uterus, cervix, colon/rectum, ovary (mucinous), and acute myeloid leukemia.
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