ANGIOGRAM
October 30, 1958 - Cleveland Clinic, U.S.A.
The first coronary angiogram was performed, unintentinally, by Dr. F. Mason Sones, Jr. (1919-1985), a pediatric cardiologist at the Cleveland Clinic. This diagnostic x-ray procedure uses dye injected to visualize blockages of the small nutrient arteries of the heart. Earlier studies on dog showed use of the the dye in coronary arteries caused heart fibrillation, so it was never tried on humans. While intending to dye a patient's diseased vessels by injecting dye only near their openings, on this occasion, the catheter insertion had inadvertently strayed into the patient's coronary artery, and about 30 cc of the dye went into the artery. Fortunately, expected heart fibrillation (requiring the opening of the patient's chest to treat) did not occur. Hence the dye could in fact be used safely, especially if in lower amounts.
SOVIET UNION WORLD'S LARGEST NUCLEAR BOMB
October 30, 1961 - Soviet Union
The Soviet Union has exploded the world's biggest bomb so far nearly 4,000 times more powerful than the atomic bomb dropped on Hiroshima in 1945. This is the latest in a series of larger and larger bombs the Soviets have been exploding over the last few years. The United Nations is appealing to both the US and the Soviet Union to end the arms race or risk destroying the planet.